doi:10.1016/j.arr.2016.08.006
Lippincott, Philadelphia Choi I-Y, Lee S, Denney DR, Lynch SG (2011) Lower levels of glutathione in the brains of secondary progressive multiple sclerosis patients measured by 1H magnetic resonance chemical shift imaging at 3 T
47,131,133,139149 These inhibitors may target upstream signaling events, such as potassium efflux, 81 mitochondrial dysfunction, 150 or lysosomal destabilization, 151,152 all critical for NLRP3 activation
Lee HK, Vaporciyan AA, Cox JD, Tucker SL, Putnam JB Jr, Ajani JA, Liao Z, Swisher SG , Roth JA, Smythe WR, Walsh GL, Mohan R, Liu HH, Mooring D, Komaki R
102 In vitro treatment with 1-h H 2 O 2 demonstrated that the catalytic activity of POLG was reduced to 50% of the original level with significantly lower DNA binding efficiency